Mechanotransduction: The Elusive Hair Cell Transduction Channel Revealed?
نویسندگان
چکیده
A family of transmembrane proteins has been shown to modulate both the calcium permeability and single-channel conductance of the vertebrate hair-cell mechanosensor, implicating them directly in inner ear mechanosensation.
منابع مشابه
HCN Channels Are Not Required for Mechanotransduction in Sensory Hair Cells of the Mouse Inner Ear
The molecular composition of the hair cell transduction channel has not been identified. Here we explore the novel hypothesis that hair cell transduction channels include HCN subunits. The HCN family of ion channels includes four members, HCN1-4. They were originally identified as the molecular correlates of the hyperpolarization-activated, cyclic nucleotide gated ion channels that carry curren...
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ورودعنوان ژورنال:
- Current Biology
دوره 23 شماره
صفحات -
تاریخ انتشار 2013